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Margaret G. Funnell, PhD; Paul M. Corballis, PhD; Michael S. Gazzaniga, PhD

Arch Neurol. 2000;57:185-189.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

INTRODUCTION

The corpus callosum is the largest fiber tract in the human brain, and plays a critical role in many aspects of interhemispheric integration. Much has been learned about the structure and connectivity of this fiber tract through anatomical studies on a variety of species. The functional implications of these anatomical findings are supported by behavioral studies on monkeys and humans with lesions of the corpus callosum.

Much of the behavioral data in humans is derived from studies on patients who have undergone callosotomy for the control of intractable epilepsy. Surgical section of the corpus callosum results in a classic disconnection syndrome characterized by a breakdown in communication between the 2 hemispheres. In the early stages of recovery from callosotomy, this communication failure can be manifested in startling ways. For example, some patients have exhibited the "alien hand" syndrome . . . [Full Text of this Article]

THE ROLE OF THE CORPUS CALLOSUM

SUBCORTICAL INFORMATION TRANSFER IN PATIENTS WITH CALLOSOTOMY

CORTICAL INFORMATION TRANSFER IN PATIENTS WITH CALLOSOTOMY

THE ROLE OF SPARED CALLOSAL FIBERS IN INTERHEMISPHERIC TRANSFER

CONCLUSIONS

The Center for Cognitive Neuroscience, Dartmouth College, Hanover, NH

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