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Susceptibility Genes and Neurological Disorders
Learning the Right Lessons From the Human Genome Project
Michael A. Grodin, MD;
Graeme T. Laurie, PhD
Arch Neurol. 2000;57:1569-1574.
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Current estimates suggest that the Human Genome Project (HGP) will be completed in 2003, by which time a comprehensive physical map of the 80,000 to 100,000 genes that constitute the entire human genome will be actualized. Few deny that this knowledge holds great promise. This advance will undoubtedly represent the beginning of a better understanding of the genetic basis for human disease processes and perhaps one day will lead to better therapies and effective cures for conditions influenced by genetic factors. Unfortunately, however, the promise of the HGP is frequently portrayed as though it will reveal the essence of humanity and unlock the secrets of our destiny and who we are as human beings. This will not happen. Such a reductionist view places too much store in the influence of genetics in determining the human condition. It is fortunate, therefore, that the . . . [Full Text of this Article]
From Boston University Schools of Medicine and Public Health, Department of Health Law, Boston, Mass (Prof Grodin); and the Edinburgh Law School, University of Edinburgh, Edinburgh, Scotland (Dr Laurie).
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