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Essential Tremor
Elan D. Louis, MD, MS
Arch Neurol. 2000;57:1522-1524.
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INTRODUCTION
Essential tremor is both a paradoxical and an elusive disorder. It is paradoxical because, while it is one of the most common neurologic disorders affecting people of all ages in all human populations,1 it was not fully described until the end of the 19th century,2 and the term itself was not consistently used by neurologists until the second half of the 20th century.3-6 It is elusive because there is no known diagnostic marker or consistently abnormal finding.
DEVELOPMENT OF THE CONCEPT THAT ESSENTIAL TREMOR IS A DISTINCT DISEASE ENTITY
The concept that there was a disease that could be labeled essential tremor developed slowly, and was the result of a series of more general concepts that had developed gradually over the preceding millennia. These concepts will be outlined below.
Early Recognition That Tremor May Be a Transient Human Physiologic State
Under certain circumstances, humans develop involuntary, repetitive, oscillatory movements. Recognition of this phenomenon dates back many thousands of years to different regions of the ancient world. For example, . . . [Full Text of this Article] Distinction Between Rest Tremor and Action Tremor Development of a Concept of Disease
CLINICAL FEATURES
GENETICS
TREATMENT
CONCLUSIONS
From the Department of Neurology and the Gertrude H. Sergievsky Center, Columbia University, New York, NY.
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