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Lewis P. Rowland, MD

Arch Neurol. 2000;57:52.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Roger Rosenberg, MD, asked us to outline the greatest triumphs of the century and important research that needs to be addressed. Can we tell?

I started neurology training in 1950. Some of the then-current technologies disappeared unpredictably, such as pneumoencephalography, direct carotid injections for angiography, frontal lobotomy, fever therapy, and tank respirators. In addition, diseases, such as paralytic poliomyelitis, measles encephalitis, Reye syndrome, and neurosyphilis, disappeared.

New technologies came unpredictably, such as computed tomography, magnetic resonance imaging, interventional neuroradiology, stereotaxic brain surgery, microsurgery, neurointensive care, positive pressure respirators, and antibiotics, arrived unpredictably. Effective drug therapy for previously untreatable diseases replaced the practice pattern Labe Scheinberg, MD, labeled ADiagnose and Adios@.

Unpredicted wonders of basic science included the DNA code and molecular genetics, which contributed to clinical research. Reciprocally, investigation of human disease contributed to basic science, for example, prions and prion diseases, triplet repeats, positional cloning, . . . [Full Text of this Article]

From the Neurological Institute, New York Presbyterian Hospital, Columbia-Presbyterian Medical Center, New York, NY.

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