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Cryptogenic Sensory Polyneuropathy
Arch Neurol. 1999;56:519-520.
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IN THIS issue of the ARCHIVES, Wolfe et al1 characterize and suggest treatment for chronic cryptogenic sensory polyneuropathy (CSPN). They define CSPN as a disorder with "pain, numbness, and tingling in the distal extremities without symptoms of weakness." Other features are symmetry, evaluation over at least 3 months, a length-dependent polyneuropathy, and no identifiable cause. Wolfe and colleagues conclude that CSPN is common, that it tends to follow a benign clinical course, and that case management should emphasize treatment of neuropathic pain using pharmacotherapeutic principles.
In my practice, these painful sensorimotor polyneuropathies are indeed common, and often an underlying cause cannot be diagnosed with certainty; therefore, the emphasis must be on treatment of pain, which is the main problem of patients with CSPN. Perhaps characterizing the syndrome, even before it is adequately classified, may be justified, because patients with CSPN are suffering, and the line between providing relief and overtreating . . . [Full Text of this Article]
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Gil I. Wolfe, Noel S. Baker, Anthony A. Amato, Carlayne E. Jackson, Sharon P. Nations, David S. Saperstein, Choon H. Cha, Jonathan S. Katz, Wilson W. Bryan, and Richard J. Barohn
Arch Neurol. 1999;56(5):540-547.
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