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Paraneoplastic Neurological Syndromes
Paraneoplastic or Neurological?
Arch Neurol. 1999;56:151-152.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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THE TERM paraneoplastic is applied to any medical condition that is caused by, or can be associated with, a malignancy other than metastasis. Webster's dictionary defines para as beside, along-side of, or associated in a subsidiary or accessory capacity. Over the past 2 decades, distinct clinical neurological entities have emerged as being paraneoplastic; these syndromes, which may affect any part of the nervous system, include subacute cerebellar degeneration, limbic encephalitis, Lambert-Eaton myasthenic syndrome, opsoclonus myoclonus, and others.1-3 Based on biological evidence, one could subdivide paraneoplastic neurological syndromes into 3 categories: (1) those whose pathogenesis is understood, (2) those that are linked to the tumor by biological data but whose pathogenesis is not yet elucidated, and (3) those (the majority) that cannot be linked to the malignancy by biological data.
Neurological disorders that belong to the first category include myelomatous polyneuropathy, Lambert-Eaton myasthenic syndrome, and myasthenia gravis. In these cases, . . . [Full Text of this Article]
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