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Molecular Neurobiology of Pain
edited by David Borsook, 369 pp, $76, Seattle, Wash, International Association for the Study of Pain Press, 1997.
Arch Neurol. 1998;55:1262-1263.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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This volume consists of summaries of papers presented at a 1996 conference held at the Massachusetts General Hospital, which focused on the new molecular approaches to the understanding of the neuronal disturbances following injury to the nervous system, ie, disturbances that obviously underlie the clinical phenomenon of pain. The authors of the chapters are, with few exceptions, basic scientistsphysiologists, geneticists, and biochemistswho are leaders in their fields. The presentations are aimed primarily at researchers in the field. Most chapters presuppose familiarity with the language of advanced basic science techniques.
Part I consists of 2 chapters on the developmental aspects of sensory neurones. The current evidence of the role of nerve growth factor and specific receptors for the survival of nociceptive and sympathetic neurones is presented. Another chapter in this part summarizes the possible roles of (1) "repulsion molecules" in the functioning of dorsal root ganglion cells; and (2) "specific genes" . . . [Full Text of this Article]
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