 |
 |

Thrombolytic Therapy in Acute Stroke
Neurologists, Get Off Your Hands!
Steven H. Horowitz, MD
Arch Neurol. 1998;55:155-157.
 |
 |
| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
|
 |
 |
I was privileged to have been one of the original principal investigators in the National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group1(NINDS rt-PA) and a coauthor of the seminal publication of the results. This study directly led to the Food and Drug Administration's approval of the thrombolytic agent, tissue-type plasminogen activator (t-PA), on June 18, 1996, as the first and, thus far, only accepted therapy specifically directed at acute ischemic stroke. As such, during the last year, I have been an invited lecturer on this treatment at a variety of medical centers, large and small. I am writing to convey my impressions of the lack of enthusiasm for this therapy exhibited by neurologists at places where I have spoken. Rather than embrace, or at least acknowledge, this as the first step in the treatment of neurology's most common serious and debilitating disease . . . [Full Text of this Article]
From the Division of Neurology, Department of Psychiatry and Neurology, University of Missouri, Columbia School of Medicine, Columbia.
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
 |
Commentary on NICE guidelines for alteplase for the treatment of acute ischaemic stroke
Lindley
Heart 2007;93:1617-1618.
FULL TEXT
Distinguishing Between Stroke and Mimic at the Bedside: The Brain Attack Study
Hand et al.
Stroke 2006;37:769-775.
ABSTRACT
| FULL TEXT
Cuyahoga County Operation Stroke Speed of Emergency Department Evaluation and Compliance With National Institutes of Neurological Disorders and Stroke Time Targets
Katzan et al.
Stroke 2003;34:994-998.
ABSTRACT
| FULL TEXT
The Imperative to Develop Dedicated Stroke Centers
Barnett and Buchan
JAMA 2000;283:3125-3126.
FULL TEXT
Trials of Thrombolysis in Acute Ischemic Stroke : Does the Choice of Primary Outcome Measure Really Matter?
Wardlaw et al.
Stroke 2000;31:1133-1135.
ABSTRACT
| FULL TEXT
Effectiveness of t-PA in acute ischemic stroke: Outcome relates to appropriateness
Buchan et al.
Neurology 2000;54:679-679.
ABSTRACT
| FULL TEXT
Stroke thrombolysis: Is tissue plasminogen activator a defibrillator for the brain?
Buchan and Feasby
CMAJ 2000;162:47-48.
FULL TEXT
Tissue-Type Plasminogen Activator
Pittman and Horowitz
Arch Neurol 1998;55:1377-1378.
FULL TEXT
Thrombolytic Therapy in Acute Stroke
Landau
Arch Neurol 1998;55:1378-1378.
FULL TEXT
|