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Thrombolytic Therapy in Acute Stroke
Neurologists, Get Off Your Hands!
Steven H. Horowitz, MD
Arch Neurol. 1998;55:155-157.
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I was privileged to have been one of the original principal investigators in the National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group1(NINDS rt-PA) and a coauthor of the seminal publication of the results. This study directly led to the Food and Drug Administration's approval of the thrombolytic agent, tissue-type plasminogen activator (t-PA), on June 18, 1996, as the first and, thus far, only accepted therapy specifically directed at acute ischemic stroke. As such, during the last year, I have been an invited lecturer on this treatment at a variety of medical centers, large and small. I am writing to convey my impressions of the lack of enthusiasm for this therapy exhibited by neurologists at places where I have spoken. Rather than embrace, or at least acknowledge, this as the first step in the treatment of neurology's most common serious and debilitating disease . . . [Full Text of this Article]
From the Division of Neurology, Department of Psychiatry and Neurology, University of Missouri, Columbia School of Medicine, Columbia.
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