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The Human Genome Project
Applications in the Diagnosis and Treatment of Neurologic Disease
Glen A. Evans, MD, PhD
Arch Neurol. 1998;55:1287-1290.
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INTRODUCTION
The Human Genome Project (HGP), an international program to decode the entire DNA sequence of the human genome in 15 years, represents the largest biological experiment ever conducted. This set of information will contain the blueprint for the construction and operation of a human being. While the primary driving force behind the genome project is the potential to vastly expand the amount of genetic information available for biomedical research, the ramifications for other fields of study in biological research, the biotechnology and pharmaceutical industry, our understanding of evolution, effects on agriculture, and implications for bioethics are likely to be profound.
The human genome is composed of 3 billion nucleotides of DNA, organized as 23 chromosomes, and contains an estimated 60000 to 70000 gene-encoded proteins. The genes constitute only about 2% to 3% of the entire DNA sequence while 40% of the sequence consists of repetitive . . . [Full Text of this Article]
METHODS
CLONING SEQUENCE PRODUCTION SEQUENCE FINISHING RELEVANCE TO CLINICAL PRACTICE AND THE PRACTICING NEUROLOGIST RELEVANCE TO THE STUDY OF NEUROSCIENCE CONCLUSIONS
From the McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center, Dallas.
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ABSTRACT
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