This Article  • Full text  • PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Contact me when this article is cited  Related Content  • Related article  • Similar articles in this journal  Topic Collections  • Bacterial Infections  • HIV/AIDS  • Encephalitis  • Meningitis  • Neuro-ophthalmology  • Ophthalmology  • Retinal/ Chorioretinal Disorders  • Dermatology  • Herpes  • Alert me on articles by topic

Joseph R. Berger, MD; Sidney Houff, MD, PhD

Arch Neurol. 2008;65(5):596-600.

Herpes simplex virus type 2 (HSV-2) infection is responsible for significant neurological morbidity, perhaps more than any other virus. Seroprevalence studies suggest that as many as 45 million people in the United States have been infected with HSV-2, and the estimated incidence of new infection is 1 million annually. Substantial numbers of these persons will manifest neurological symptoms that are generally, although not always, mild and self-limited. Despite a 50% genetic homology between HSV-1 and HSV-2, there are significant differences in the clinical manifestations of these 2 viruses. We herein review the neurological complications of HSV-2 infection.

Author Affiliations: Department of Neurology, University of Kentucky College of Medicine, Lexington.

RELATED ARTICLE

This Month in Archives of Neurology
Arch Neurol. 2008;65(5):572-573.
FULL TEXT