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Ludivine Chalumeau-Lemoine, MD; Fabrice Chretien, MD, PhD; Anne Gaëlle Si Larbi, MD; Pierre Brugieres, MD; Françoise Gray, MD, PhD; Christian Brun-Buisson, MD; Alain Creange, MD, PhD

Arch Neurol. 2006;63:591-593.

We describe a patient who suffered from an unusually severe form of neuromyelitis optica with a hyperacute time-course evolution requiring mechanical ventilation within 3 days. The patient died after 72 days and autopsy showed major spinal cord, optic nerve, and brainstem necrosis, and multifocal necrotic lesions on the cerebellum and cerebral white matter.

Author Affiliations: Medical Reanimation Service (Drs Chalumeau-Lemoine, Gaëlle Si Larbi, and Brun-Buisson), Pathology Department and National Institute for Health Research (Dr Chretien), Medical Imagery Department (Dr Brugieres), and Neurology Service (Dr Creange), Henri Mondor Hospital, University of Paris XII, Créteil, France; Pathology Department, Lariboisière Hospital, Paris, France (Dr Gray).

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