This Article  • Full text  • PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (8)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Topic Collections  • Neurogenetics  • Statistics and Research Methods  • Genetic Counseling/ Testing/ Therapy  • Alert me on articles by topic  Social Bookmarking   What's this?

Applications and Pitfalls

Hassan M. Fathallah-Shaykh, MD

Arch Neurol. 2005;62:1669-1672.

Microarrays are simple assays that measure the relative expression levels of tens of thousands of genes. Excitement about their importance and potential contributions to biology and medicine has been intense. Nonetheless, recent insights into the limitations and pitfalls of microarrays have led to caution about data interpretation. Microarrays are very useful but they are also very misleading; better data analysis tools are needed to improve accuracy.

Author Affiliations: Department of Neurological Sciences, Section of Neuro-oncology, Rush University Medical Center, Chicago, Ill.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Integrating Molecular Biology into the Veterinary Curriculum
Ryan and Sweeney
jvme 2007;34:658-673.
ABSTRACT | FULL TEXT  

DNA Microarrays in Herbal Drug Research
Chavan et al.
Evid Based Complement Alternat Med 2006;3:447-457.
ABSTRACT | FULL TEXT  

Pituitary tumours: findings from whole genome analyses.
Farrell
Endocr Relat Cancer 2006;13:707-716.
ABSTRACT | FULL TEXT  

Molecular biology for the clinician: understanding current methods.
Chandler and Colitz
Journal of the American Animal Hospital Association 2006;42:326-335.
ABSTRACT | FULL TEXT