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  Vol. 61 No. 7, July 2004 TABLE OF CONTENTS
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Ischemic Stroke During Sexual Intercourse

A Report of 4 Cases in Persons With Patent Foramen Ovale

Kyra Becker, MD; Elaine Skalabrin, MD; Danial Hallam, MD; Edward Gill, MD

Arch Neurol. 2004;61:1114-1116.

Background  The association between patent foramen ovale (PFO) and stroke risk in young adults is controversial and poorly understood. Paradoxical embolization through a PFO represents a possible mechanism by which PFO might predispose to stroke.

Objective  To describe 4 patients with PFO who experienced the onset of ischemic stroke during sexual intercourse.

Design  Case series.

Setting  Tertiary referral stroke clinic.

Patients  Consecutive patients experiencing stroke during intercourse.

Results  All 4 patients were found to have PFO. Despite a thorough evaluation, no other etiology for stroke was identified.

Conclusion  We suggest that paradoxical embolization through a PFO due to elevated intrathoracic pressure during sexual activity could be a potential mechanism for stroke in these patients.


From the Departments of Neurology (Dr Becker), Radiology (Dr Hallam), and Medicine (Dr Gill), Harborview Medical Center, University of Washington School of Medicine, Seattle; and the Department of Neurology, University of Utah School of Medicine, Salt Lake City (Dr Skalabrin).



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