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An Ongoing Discussion About a Disease Entity

Irene M. Bronner, MD; Wim H. J. P. Linssen, MD, PhD; Marjon F. G. van der Meulen, MD; Jessica E. Hoogendijk, MD, PhD; Marianne de Visser, MD, PhD

Arch Neurol. 2004;61:132-135.

Since its first description more than a century ago, there has been much debate about the diagnostic entity polymyositis. Because initial observations were of individuals with dermatomyositis, it appeared that polymyositis was not possible without skin lesions. Distinctive clinical and histologic features of polymyositis were not established until the late 20th century. The identification of inclusion body myositis as a distinct entity has further refined nosographic classification.

From the Department of Neurology, Sint Lucas Andreas Hospital, Amsterdam, the Netherlands (Drs Bronner and Linssen); University Medical Center Utrecht, Utrecht, the Netherlands (Drs van der Meulen and Hoogendijk); and Academic Medical Center, University of Amsterdam (Dr de Visser), Amsterdam.

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