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Incidence of Acute Femoral Neuropathy Following Renal Transplantation
Khema Ram Sharma, MD;
Jonathan Cross, MD;
Fernando Santiago, MD;
D. Ram Ayyar, MD;
George Burke III, MD
Arch Neurol. 2002;59:541-545.
Background Case reports exist of femoral neuropathy following renal transplantation
(RTSP) with possible pathophysiology, including direct compression and nerve
ischemia. However, the occurrence of acute femoral neuropathy (AFN) following
RTSP has not been studied prospectively.
Objective To determine the occurrence of AFN following RTSP.
Methods We prospectively studied the occurrence of AFN following RTSP from June
1, 1998, to October 31, 1999. A total of 184 RTSPs were performed during this
period. All the patients had end-stage renal failure and had effective hemodialysis
before RTSP. All patients with AFN underwent neurologic examination, nerve
conduction and electromyographic studies (5 to 7 days after the onset of symptoms),
and magnetic resonance imaging or computed tomography of pelvis and lumbosacral
spine within 24 hours of onset of symptoms.
Results Four (2.2%) of 184 patients developed AFN (ipsilateral to the RTSP surgery)
postoperatively between 24 (3 patients) and 48 hours. All the patients achieved
good renal function after RTSP. All the patients had excellent recovery of
motor function in 4 to 9 months.
Conclusion We believe that AFN following RTSP is an uncommon (2.2%) complication
from which patients have an excellent chance of recovery.
From the Department of Neurology, University of Miami School of Medicine,
Miami, Fla.
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