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Ernest Palomeras, MD; Pilar Sanz, MD; Antonio Cano, MD; Pilar Fossas, MD

Arch Neurol. 2000;57:570-571.

We present a 68-year-old patient with essential tremor who was treated with propranolol hydrochloride (80 mg daily) and gabapentin (900 mg daily) after a history of mild success of gabapentin alone in relieving his symptoms. The patient had several daily episodes of paroxysmal dystonic movements in both hands. After reducing the propranolol dose to 40 mg daily, the dystonic movements resolved. This case suggests a synergistic effect between propranolol and gabapentin.

From the Unit of Neurology, Hospital de Mataró, Mataró, Spain.

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