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Michael F. Finkel, MD

Arch Neurol. 2000;57:1519-1520.

Objective  To report the successful treatment of primary orthostatic tremor in a 76-year-old man.

Background  Primary orthostatic tremor is a rare condition, with few reports describing therapies. Established therapies had previously failed in our patient.

Methods  Using an evidence-based evaluation of treatments via MEDLINE's GRATEFUL MED search engine, a therapeutic option was determined during the first consultation with the patient, and pramipexole therapy was initiated.

Results  The therapy proved effective, and the patient had relief from his symptoms for the first time in 6 years.

Conclusion  Pramipexole is a potential therapy for primary orthostatic tremor.

From the Department of Neurology, Cleveland Clinic Naples, Naples, Fla.

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