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Bernard J. Sweeney, MRCPI; Jane Edgecombe, MRCP; Duncan R. Churchill, MRCP; Robert F. Miller, MRCP; Michael J. G. Harrison, FRCP

Arch Neurol. 1994;51(7):723-725.

Abstract
Objective
To describe the association between acute choreoathetosis/ballismus and hypoglycemia related to pentamidine therapy in a patient with the acquired immunodeficiency syndrome.

Design
A single case report.

Measures
Clinical observation, laboratory analysis of blood and cerebrospinal fluid, and magnetic resonance imaging of brain.

Results
No association was found apart from hypoglycemia. The abnormal movements and hypoglycemia did not recur following cessation of pentamidine.

Conclusions
Hypoglycemia related to pentamidine therapy can cause neurologic disorders in patients with the acquired immunodeficiency syndrome.

Author Affiliations
From the Academic Departments of Neurology (Drs Sweeney and Harrison) and Medicine (Drs Edgecombe, Churchill, and Miller), University College London (England) Medical School.