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Opportunistic Cerebral Vasculopathy and Stroke in Patients With the Acquired Immunodeficiency Syndrome
Karl D. Kieburtz, MD;
Thomas A. Eskin, MD;
Leena Ketonen, MD, PhD;
Michael J. Tuite, MD
Arch Neurol. 1993;50(4):430-432.
Abstract
Objective. —To describe an unusual cause of stroke in patients with the acquired immunodeficiency syndrome.
Design. —An observational case series of hospitalized patients with subsequent autopsy.
Measures. —Clinical, radiological, and pathological examinations were performed.
Results. —In three of 14 patients with stroke, the infarctions were secondary to an opportunistic vasculopathy caused by Candida albicans, cytomegalovirus, or lymphoma.
Conclusion. —Opportunistic conditions may lead to vascular abnormalities and subsequent stroke in patients with the acquired immunodeficiency syndrome.
Author Affiliations
From the Departments of Neurology (Dr Kieburtz), Pathology (Dr Eskin), and Radiology (Drs Ketonen and Tuite), University of Rochester (NY) Medical Center.
Footnotes
Accepted for publication September 8, 1992.
Presented in part at the annual meeting of the American Academy of Neurology, San Diego, Calif, May 5, 1992.
Reprint requests to Department of Neurology, Box 673, 601 Elmwood Ave, Rochester, NY 14642 (Dr Kieburtz).
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