Early Guillain-Barre syndrome without inflammation
A. H. Ropper and L. Adelman
Division of Neurology, St Elizabeth's Hospital, Boston, MA 02135.
A patient with typical acute Guillain-Barre syndrome died 72 hours after
his first symptoms occurred, and an autopsy was performed 8 hours after his
death. Extensive sampling of cranial and peripheral nerves, sensory
ganglia, and autonomic nerves showed only minimal inflammatory lymphocytic
and macrophage infiltrates. This case, one of the earliest studied
extensively, represents an extreme example of a noninflammatory mechanism
that has been proposed in some cases of Gullain-Barre syndrome.
