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Progressive Amusia and Aprosody
Christian Confavreux, MD;
Bernard Croisile, MD;
Paul Garassus, MD;
Gilbert Aimard, MD;
Marc Trillet, MD
Arch Neurol. 1992;49(9):971-976.
Abstract
• We report a case of slowly progressive amusia and aprosody in association with orofacial and eyelid apraxias. The patient was independent in daily living activities. Insight, judgment, and behavior were intact. Her language was normal, and she demonstrated no limb, dressing, or constructional apraxia. She had no prosopagnosia, no visuospatial disturbances, and no memory impairment. Imaging studies (computed tomography, magnetic resonance imaging, single photon emission computed tomography) indicated a selective disorder of the right frontal and temporal regions. Review of the literature shows an increasing number of reports of this degenerative syndrome affecting the left dominant hemisphere and language areas, whereas cases of the syndrome affecting the right hemisphere are rare. To our knowledge, this is the first case in which aprosody and amusia were associated with a focal cortical degeneration.
Author Affiliations
From the Neurology Clinic, Hôpital Neurologique, Lyon, France.
Footnotes
Accepted for publication January 10, 1992.
Reprint requests to Neurology Clinic, Hôpital Neurologique, 59 Boulevard Pinel, 69003 Lyon, France (Dr Confavreux).
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