 |
 |

Matching-to-Sample Deficits in Patients With Senile Dementias of the Alzheimer and Lewy Body Types
Arjun Sahgal, PhD;
Peter H. Galloway, BMedSci;
Ian G. McKeith, MRCPsych;
Stephen Lloyd, BSc;
Julia H. Cook, RMN;
I. Nicol Ferrier, MD;
James A. Edwardson, PhD
Arch Neurol. 1992;49(10):1043-1046.
Abstract
Using a computerized matching-to-sample task, nonverbal visual recognition memory was studied in two groups of patients suffering from senile dementia of the Alzheimer type or the recently described senile dementia of the Lewy body type. The patients' cognitive abilities had been shown to be similar according to a number of standard psychometric tests. The two groups did not differ with respect to simultaneous matching-to-sample performance, although both were impaired relative to control. The group with senile dementia of the Lewy body type was severely impaired, relative to the group with senile dementia of the Alzheimer type, when delays (delayed matching to sample) were introduced. The findings suggest that short-term mnemonic processes, mediated by temporal lobe structures, could be more severely affected in senile dementia of the Lewy body type.
Author Affiliations
From the Medical Research Council Neurochemical Pathology Unit (Drs Sahgal, McKeith, Ferrier, and Edwardson and Messrs Galloway and Lloyd) and the University Department of Old Age Psychiatry (Dr McKeith and Ms Cook), Newcastle General Hospital, and the Department of Psychiatry, Royal Victoria Infirmary (Dr Ferrier), Newcastle upon Tyne, England.
Footnotes
Accepted for publication April 27, 1992.
Reprint requests to Medical Research Council Neurochemical Pathology Unit, Newcastle General Hospital, Westgate Road, Newcastle upon Tyne, England NE4 6BE (Dr Sahgal).
CiteULike Connotea Del.icio.us Digg Reddit Technorati Twitter
What's this?
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
 |
Higher cortical deficits influence attentional processing in dementia with Lewy bodies, relative to patients with dementia of the Alzheimer's type and controls
Bradshaw et al.
J. Neurol. Neurosurg. Psychiatry 2006;77:1129-1135.
ABSTRACT
| FULL TEXT
Dementia With Lewy Bodies Studied With Positron Emission Tomography
Cordery et al.
Arch Neurol 2001;58:505-508.
ABSTRACT
| FULL TEXT
Semantic memory is impaired in both dementia with Lewy bodies and dementia of Alzheimer's type: a comparative neuropsychological study and literature review
Ralph et al.
J. Neurol. Neurosurg. Psychiatry 2001;70:149-156.
ABSTRACT
| FULL TEXT
Perception, attention, and working memory are disproportionately impaired in dementia with Lewy bodies compared with Alzheimer's disease
Calderon et al.
J. Neurol. Neurosurg. Psychiatry 2001;70:157-164.
ABSTRACT
| FULL TEXT
A Review of Lewy Body Disease, an Emerging Concept of Cortical Dementia
Papka et al.
J. Neuropsychiatry Clin. Neurosi. 1998;10:267-279.
ABSTRACT
| FULL TEXT
Neuropsychiatric Manifestations of Diffuse Lewy Body Disease
Beck
J Geriatr Psychiatry Neurol 1995;8:189-196.
ABSTRACT
|