Nervous system Lyme borreliosis--revisited [corrected; erratum to be published]
M. F. Finkel, J. J. Halperin and M. J. Finkel
Department of Neurology, Midelfort Clinic, Eau Claire, Wis.
A great deal of confusion surrounds the diagnosis, clinical phenomenology,
and treatment of Lyme borreliosis. Most diagnostic methods currently in use
are indirect and do not differentiate between prior exposure and current
infection. A critical review of the literature permits the characterization
of a distinct set of neurologic disorders that are almost certainly caused
by this infection and their differentiation from the plethora of syndromes
that have been anecdotally linked to infection, but in which causality has
never been established. This article describes the range of clinical
disorders associated with Lyme borreliosis, provides an overview of current
approaches to diagnosis, and reviews current treatment protocols.