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The Asymptomatic Cervical Bruit Study Group

Arch Neurol. 1991;48(7):683-686.

Abstract
• We report a multicenter study in progress involving a prospective follow-up of asymptomatic patients with cervical bruits. The project consists of two components. All patients meeting clinical criteria for eligibility undergo duplex ultrasonography at the time of entry into the study. Those with a carotid stenosis of 50% or greater are enrolled in a randomized placebo-controlled trial of aspirin. All other patients are followed up in a natural history study, also involving biannual clinical and duplex ultrasonographic examinations. Both clinical and anatomic outcomes are assessed. The project consists of a 3-year accrual phase and a 3-year follow-up phase with completion planned for May 1994. Total anticipated enrollment is 588 patients.

Footnotes
Accepted for publication January 16, 1991.

A complete listing of participants in this research study appears at the end of this article.

Reprint requests to the Division of Neurology, Room 7864, Livingston Hall, The Montreal General Hospital, 1650 Cedar Ave, Montreal, Quebec, H3G 1A4 Canada (Robert Côté, MD, FRCPC).

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