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Daniel K. Kido, MD; Robert J. Panzer, MD; Jerzy Szumowski, PhD; Joshua Hollander, MD; Leena M. Ketonen, MD, PhD; Ahmad Monajati, MD; Kenneth Ouriel, MD; James V. Manzione, MD, DMD; Charles L. Dumoulin, PhD; Steven P. Souza, PhD; Jill L. Katz, RN; Barbara M. Rothenberg, MPA, MA

Arch Neurol. 1991;48(5):484-489.

Abstract
• We evaluated the images of 60 carotid artery bifurcations in 31 patients suspected to have carotid artery disease who underwent invasive carotid angiography and combined two-dimensional, phase-sensitive and a gradient-echo magnetic resonance angiography. The phase scans consisted of seven serial projections that were obtained at 20° intervals (11.0 minutes) around the carotid bifurcation; the gradient-echo (GRASS) scans were composed of 11 axial images (2.4 minutes) acquired through the bifurcation. The two magnetic resonance angiographic techniques yielded complementary pieces of information and were used together to compare magnetic resonance angiography with invasive angiography. Comparison of magnetic resonance and invasive angiograms of the 60 carotid arteries shows that the sensitivity (86%) and specificity (92%) of the magnetic resonance angiographic techniques we used to diagnose clinically significant carotid stenosis approach but do not reach those of invasive angiography.

Author Affiliations
From the Departments of Diagnostic Radiology (Drs Kido, Ketonen, Monajati, and Manzione and Mss Katz and Rothenberg), Medicine (Dr Panzer), Neurology (Dr Hollander), and Surgery (Dr Ouriel), University of Rochester (NY) Medical Center; the Department of Diagnostic Radiology, Oregon Health Sciences University, Portland (Dr Szumowski); and General Electric Corporate Research and Development Center, Schenectady, NY (Drs Dumoulin and Souza). Dr Kido is now with the Mallinckrodt Institute of Radiology, Washington University Medical Center, St Louis, Mo.

Footnotes
Accepted or publication October 8,1990.

Presented in part at the 27th Annual Meeting of the American Society of Neuroradiology, Orlando, Fla, March 23,1989.

Reprint requests to the Mallinckrodt Institute of Radiology, Washington University Medical Center, 510 S Kingshighway Blvd, St Louis, MO 63110 (Dr Kido).

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