 |
|
Lymphomatous PolyneuropathyBiopsy of Clinically Involved Nerve and Successful Treatment
David A. Krendel, MD;
Robert L. Stahl, MD;
Wing C. Chan, MD
Arch Neurol. 1991;48(3):330-332.
Abstract
• We present a patient with large-cell lymphoma in remission who, over several weeks, developed widespread multifocal polyneuropathy. There was involvement of all four limbs, most severely the left upper extremity that had become useless. Biopsy of the left saphenous nerve within an area of sensory loss showed lymphoma in the endoneurium. There was no other evidence of recurrent lymphoma despite extensive investigation, including bone marrow, lumbar puncture, magnetic resonance imaging of the spine, and computed tomography of the abdomen and pelvis. Intensive systemic chemotherapy was accompanied by nearly complete recovery. Biopsy of a symptomatic nerve is preferable to routine sural nerve biopsy in this condition because of its patchy distribution. Treatment with systematic chemotherapy can be effective.
Author Affiliations
From the Department of Neurology (Dr Krendel), Division of Hematology, Department of Medicine (Dr Stahl), and Division of Hematopathology, Department of Pathology (Dr Chan), Emory University School of Medicine, Atlanta, Ga.
Footnotes
Accepted for publication April 30, 1990.
Reprint requests to the Department of Neurology, Emory Clinic, 1365 Clifton Rd NE, Atlanta, GA 30322 (Dr Krendel).
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter
What's this?
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
Lymphoma Involving the Ulnar Nerve: Sonographic Findings
Choi et al.
J Ultrasound Med 2008;27:1527-1531.
FULL TEXT
Neurolymphomatosis
Baehring et al.
Neuro Oncol Duke 2003;5:104-115.
ABSTRACT
Neurolymphomatosis of the lumbar plexus: High-resolution MR neurography findings
Moore et al.
Neurology 2001;57:740-742.
FULL TEXT
|
