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Frontal Impairment and Hypoperfusion in Neuroacanthocytosis
Florence Delecluse, MD;
Jeanine Deleval, MS;
Jean-Marie Gérard, MD;
Alex Michotte, MD;
Diederik Zegers de Beyl, MD
Arch Neurol. 1991;48(2):232-234.
Abstract
Cerebral blood flow tomography, by xenon 133 inhalation or HMPAO (99mTc-d, 1-hexamethyl-propylene amine oxime) technetium Tc 99m injection, revealed a severe hypoperfusion in both frontal lobes of a 40-year-old woman with confirmed neuroacanthocytosis. This finding occurred in conjunction with neuropsychological deficits consistent with selective frontal lobe dysfunction. This observation is the first documentation of this type of dementia in neuroacanthocytosis.
Author Affiliations
From the Neurology Service, Erasme Hospital, University of Brussels (Belgium).
Footnotes
Accepted for publication March 16, 1990.
Reprint requests to Department of Neurology, Erasme Hospital, 808 route de Lennik, B-1070 Brussels, Belgium (Dr Delecluse).
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