Neurologic complications of nonneuronopathic Gaucher's disease
R. P. Grewal, S. H. Doppelt, M. A. Thompson, D. Katz, R. O. Brady and N. W. Barton
Developmental and Metabolic Neurology Branch, National Institute of Neurological Disorders and Stroke (NINDS), National Institutes of Health, Bethesda, MD 20892.
We describe eight patients with type 1 Gaucher's disease who developed
neurologic complications that were secondary to systemic features of the
illness. Four patients experienced neurologic difficulties because of
coagulopathy, and the other four patients had involvement of the nervous
system secondary to skeletal disease. Early recognition of these
complications in patients with type 1 Gaucher's disease may lead to
improved neurologic outcome.
