Binswanger's disease and normal-pressure hydrocephalus. Clinical and neuropsychological comparison
R. Gallassi, A. Morreale, P. Montagna, T. Sacquegna, R. Di Sarro and E. Lugaresi
Institute of Neurology, University of Bologna, Italy.
We investigated the clinical and cognitive aspects of patients with
normal-pressure hydrocephalus and possible Binswanger's disease. We studied
19 patients with normal-pressure hydrocephalus and 19 patients with
Binswanger's disease, comparing them with the same number of matched
controls. The patients with normal-pressure hydrocephalus had a later age
and more frequent gait disturbance at the onset, shorter duration of the
illness, rare signs of vascular disturbances, and more frequent severe
mental deterioration. Ventricular enlargement may play a role in
determining the more rapid and worse clinical course of normal-pressure
hydrocephalus.
