This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Renée Malouf, MD; Germaine Jacquette, MD; Jay Dobkin, MD; John C. M. Brust, MD

Arch Neurol. 1990;47(9):1002-1007.

Abstract
• Previous studies of human immunodeficiency virus-related neurologic disease have been either retrospective or have included mostly homosexual patients. We sought to determine (1) the true prevalence of neurologic abnormalities in patients with acquired immunodeficiency syndrome or lymphadenopathy acquired immunodeficiency-related complex, and (2) whether differences in prevalence or type of neurological abnormality exist between parenteral drug abusers and non-parenteral drug abusers. We prospectively evaluated 190 adult inpatients with either acquired immunodeficiency syndrome (129) or lymphadenopathy acquired immunodeficiency-related complex (61); 151 (80%) were parenteral drug abusers, and 172 patients (91%) had neurologic symptoms or signs. There was no significant difference in prevalence of neurologic disease between parenteral drug abusers and non-parenteral drug abusers, or between patients with acquired immunodeficiency syndrome and those with lymphadenopathy acquired immunodeficiencyrelated complex. The prevalence of neurologic symptoms in these patients with lymphadenopathy acquired immunodeficiency-related complex and acquired immunodeficiency syndrome is the highest reported to date and appears to reflect the prospective nature of the study.

Author Affiliations
From the Departments of Neurology (Drs Malouf and Brust), and Medicine (Drs Jacquette and Dobkin), Harlem Hospital Center and Columbia University College of Physicians and Surgeons, and the New York City Health and Hospitals Corporation, New York, NY.

Footnotes
Accepted for publication December 22, 1989.

Reprint requests to Department of Neurology, Harlem Hospital Center, 506 Lenox Ave, New York, NY 10037 (Dr Malouf).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Stroke and HIV Infection * Response
Restrepo et al.
Stroke 2003;34 :e176-e177.
FULL TEXT  

Prevalence of peripheral neuropathy in injection drug users
Berger et al.
Neurology 1999;53:592-592.
ABSTRACT | FULL TEXT  

Neurologic and Neuropsychological Manifestations of Human Immunodeficiency Virus Infection in Intravenous Drug Users Without Acquired Immunodeficiency Syndrome: Relationship to Head Injury
Marder et al.
Arch Neurol 1992;49:1169-1175.
ABSTRACT