Magnetic resonance imaging and neurobehavioral correlates in schizencephaly
A. S. Aniskiewicz, N. L. Frumkin, D. E. Brady, J. B. Moore and A. Pera
Department of Radiology, Michigan State University, East Lansing.
We studied three patients with schizencephaly and related the results of
comprehensive neuropsychologic and speech/language assessments to the
severity and location of the brain malformations as appreciated by magnetic
resonance imaging. Level of general intellectual functioning related to the
amount of brain tissue involved, and variations in specific neurobehavioral
abilities reflected the location of the brain malformation and the prenatal
onset of the disorder. The overall findings emphasize the importance of
comprehensive neuropsychologic and speech/language studies for appreciating
the impact of prenatal neural insult on the functional reorganization of
the brain and subsequent neurobehavioral functioning.
