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  Vol. 47 No. 7, July 1990 TABLE OF CONTENTS
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Autosomal Dominant Cramping Disease

Kenneth Ricker, MD; Richard T. Moxley III, MD

Arch Neurol. 1990;47(7):810-812.


Abstract

• A family was studied in which four generations (16 of 41 members) suffered from painful recurrent muscle cramping. A clear pattern of autosomal dominant inheritance was noted. The cramping first developed during adolescence or early adulthood. Electromyographic analysis indicated a neurogenic origin. The cramps seemed to be due to dysfunction of the motor neurons. The mechanisms underlying this alteration are unclear and require further investigation.



Author Affiliations

From the Department of Neurology, University of Würzburg, West Germany (Dr Ricker); and the Departments of Neurology and Pediatrics, University of Rochester (NY) School of Medicine and Dentistry (Dr Moxley).


Footnotes

Accepted for publication October 27, 1989.

Reprint requests to Neurologische Universitätsklinik, Josef-Schneider-Strasse 11, D-8700 Würzburg, West Germany (Dr Ricker).



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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Autosomal dominant muscle cramp syndrome in a Japanese family
Chiba et al.
J. Neurol. Neurosurg. Psychiatry 1999;67:116-119.
ABSTRACT | FULL TEXT  





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