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Kenneth Ricker, MD; Richard T. Moxley III, MD

Arch Neurol. 1990;47(7):810-812.

Abstract
• A family was studied in which four generations (16 of 41 members) suffered from painful recurrent muscle cramping. A clear pattern of autosomal dominant inheritance was noted. The cramping first developed during adolescence or early adulthood. Electromyographic analysis indicated a neurogenic origin. The cramps seemed to be due to dysfunction of the motor neurons. The mechanisms underlying this alteration are unclear and require further investigation.

Author Affiliations
From the Department of Neurology, University of Würzburg, West Germany (Dr Ricker); and the Departments of Neurology and Pediatrics, University of Rochester (NY) School of Medicine and Dentistry (Dr Moxley).

Footnotes
Accepted for publication October 27, 1989.

Reprint requests to Neurologische Universitätsklinik, Josef-Schneider-Strasse 11, D-8700 Würzburg, West Germany (Dr Ricker).

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