Vaccine-associated paralytic poliomyelitis. Regional case series and review
H. Querfurth and P. D. Swanson
Division of Neurology, University of Washington School of Medicine, Seattle 98195.
We present 10 cases of vaccine-associated paralytic poliomyelitis from
Washington State to better acquaint physicians with the signs and symptoms
of this condition. Diagnosis may be delayed, and milder cases may be
overlooked, owing to the unfamiliarity of physicians with the condition.
Based on these 10 cases, a rate of 6.4 cases (recipient plus contact) per
million live births is estimated for the period 1966 through 1988 in
Washington. This rate is higher than calculated for the nation as a whole.
The explantation for this difference is unknown, although several
possibilities exist, including case clustering.
