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  Vol. 47 No. 3, March 1990 TABLE OF CONTENTS
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The Use of Sensory Action Potentials in the Diagnosis of Peripheral Nerve Disease

Jeremy M. Shefner, MD; David M. Dawson, MD

Arch Neurol. 1990;47(3):341-348.


Abstract

• We review the different measurements that can be derived from recordings of compound sensory action potentials, and describe how less commonly measured aspects may be of use in clinical situations. In addition to the frequently obtained maximum conduction velocity and amplitude, minimum conduction velocity may be measured if near nerve electrodes and response averaging are used. Minimum conduction velocity is a sensitive measure of both axonal and demyelinating peripheral nerve pathology. Activity-dependent conduction is another aspect of sensory conduction that may provide additional information for the clinician. Refractory period of transmission has been used to diagnose subtle demyelinating lesions, as well as some axonal disorders. Supernormal period and the conduction of trains of stimuli may also be useful, although, at present, they remain predominantly research tools.



Author Affiliations

From the Division of Neurology, Brigham and Women's Hospital, the Neurology Service, Brockton-West Roxbury Veterans Administration Medical Center, and the Department of Neurology, Harvard Medical School, Boston, Mass.


Footnotes

Accepted for publication June 7, 1989.

Reprint requests to Neurophysiology Laboratories, Brigham and Women's Hospital, 75 Francis St, Boston, MA 02115 (Dr Shefner).



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