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P. Labrune, MD; S. Chatelon, MD; P. Huguet, MD; M. Odievre, MD

Arch Neurol. 1990;47(11):1243-1244.

Abstract
• Five children with hereditary fructose intolerance developed symptoms of neurological impairment. In three of them, neurological involvement was related to the acute hepatic toxicity of fructose (hypoglycemia, abnormal coagulation, cardiovascular collapse); in the other two, such a relationship could not be demonstrated. Neurological impairment is not classic in hereditary fructose intolerance, but its occurrence in the acute phase of the disease is possible and does not constitute an argument against the diagnosis.

Author Affiliations
From the Service de Pédiatrie, Hôpital Antoine Béclère, Clamart, France.

Footnotes
Accepted for publication February 12, 1990.

Reprint requests to the Service de Pédiatrie, Hôpital Antoine Béclère, 157 rue de la Porte de Trivaux, 92141 Clamart Cedex, France (Dr Labrune).

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