Screening for early dementia using memory complaints from patients and relatives
J. McGlone, S. Gupta, D. Humphrey, S. Oppenheimer, T. Mirsen and D. R. Evans
University Hospital, London, Ontario, Canada.
This study examined whether the subjective impression of memory function
might differentiate healthy elderly subjects from patients with memory
complaints, and whether memory complaints differed between patients with
and without a dementing illness. Both self-assessment and relatives'
responses on a new memory questionnaire differentiated patient groups from
control subjects. The relatives' form measuring deterioration in memory
function over time identified dementing individuals from those with
non-dementing causes for their memory complaints. Factor analysis indicated
that patients' memory complaints correlated with depression rather than
objective memory performance, while relatives' ratings correlated with
objective memory scores, not depression. Stepwise discriminant function
analyses showed that objective memory testing greatly improved specificity
but not sensitivity of the subjective memory questionnaire alone.
Does This Patient Have Dementia?
Holsinger et al.
JAMA 2007;297:2391-2404.
ABSTRACT
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Investigating poor insight in Alzheimer's disease: A survey of research approaches
Robertsson et al.
Dementia 2007;6:45-61.
ABSTRACT
Memory complaints are related to Alzheimer disease pathology in older persons.
Barnes et al.
Neurology 2006;67:1581-1585.
ABSTRACT
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Relationship of Self-Perceptions of Memory and Worry to Objective Measures of Memory and Cognition in the General Population
Podewils et al.
Psychosomatics 2003;44:461-470.
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Neuropsychological Predictors of Everyday Memory and Everyday Functioning in Patients with Mild Alzheimer's Disease
Cahn-Weiner et al.
J Geriatr Psychiatry Neurol 2003;16:84-89.
ABSTRACT
Diagnostic Evaluation of Elderly Patients with Mild Memory Problems
Karlawish and Clark
ANN INTERN MED 2003;138:411-419.
ABSTRACT
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Screening for multiple sclerosis cognitive impairment using a self-administered 15-item questionnaire
Benedict et al.
Mult Scler 2003;9:95-101.
ABSTRACT
Cerebral white matter lesions and subjective cognitive dysfunction: The Rotterdam Scan Study
de Groot et al.
Neurology 2001;56:1539-1545.
ABSTRACT
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Mild Cognitive Impairment Represents Early-Stage Alzheimer Disease
Morris et al.
Arch Neurol 2001;58:397-405.
ABSTRACT
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Association Between Memory Complaints and Incident Alzheimer's Disease in Elderly People With Normal Baseline Cognition
Geerlings et al.
Am. J. Psychiatry 1999;156:531-537.
ABSTRACT
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Mild Cognitive Impairment: Clinical Characterization and Outcome
Petersen et al.
Arch Neurol 1999;56:303-308.
ABSTRACT
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North of England evidence based guidelines development project: guideline for the primary care management of dementia
Eccles et al.
BMJ 1998;317:802-808.
FULL TEXT
Prevalence of intellectual dysfunctioning and its correlates in a community-residing elderly population
Nakanishi et al.
Scand J Public Health 1998;26:198-203.
ABSTRACT
Metamemory in Temporal Lobe Epilepsy
Deutsch et al.
Assessment 1996;3:255-263.
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