This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Janis M. Peyser, PhD; Stephen M. Rao, PhD; Nicholas G. LaRocca, PhD; Edith Kaplan, PhD

Arch Neurol. 1990;47(1):94-97.

Abstract
• Acquisition of scientific information regarding the neuropsychological aspects of multiple sclerosis has been hampered by studies using small, inadequately described patient and control samples and a wide array of cognitive test procedures that hinder multicenter data pooling. Based on a review of key issues of clinical need and experimental interest, research guidelines are proposed for investigations in this burgeoning research area. The guidelines include suggestions for sampling methods, population characterization, and control groups as well as a recommended core battery of neuropsychological tests for use in this population. It is hoped that these guidelines will advance knowledge about the neuropsychology of multiple sclerosis by helping to promote sound experimental design, facilitate cross-study comparison, and encourage multicenter collaborative efforts.

Author Affiliations
From the Departments of Psychology and Psychiatry, University of Vermont and the College of Medicine, Burlington, Vt (Dr Peyser); Department of Neurology, Medical College of Wisconsin, Milwaukee (Dr Rao); Department of Neurology and Psychiatry, Albert Einstein College of Medicine, Bronx, NY (Dr LaRocca); and Departments of Neurology and Psychiatry, Boston (Mass) University School of Medicine (Dr Kaplan).

Footnotes
Accepted for publication June 28, 1989.

Reprint requests to the Research and Medical Programs Department, National Multiple Sclerosis Society, 205 E 42nd St, New York, NY 10017.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

A longitudinal fMRI study of the paced auditory serial addition task
Cardinal et al.
Mult Scler 2008;14:465-471.
ABSTRACT  

Polymorphisms of the cannabinoid 1 receptor gene and cognitive impairment in multiple sclerosis
Woolmore et al.
Mult Scler 2008;14:177-182.
ABSTRACT  

Cognitive dysfunction in patients with clinically isolated syndromes or newly diagnosed multiple sclerosis
Glanz et al.
Mult Scler 2007;13:1004-1010.
ABSTRACT  

The Rao's Brief Repeatable Battery and Stroop test: normative values with age, education and gender corrections in an Italian population
Amato et al.
Mult Scler 2006;12:787-793.
ABSTRACT  

Cognitive functioning in children and adolescents with multiple sclerosis
MacAllister et al.
Neurology 2005;64:1422-1425.
ABSTRACT | FULL TEXT  

Cognitive deficit associated with cholinergic and nerve growth factor down-regulation in experimental allergic encephalomyelitis in rats
D'Intino et al.
Proc. Natl. Acad. Sci. USA 2005;102:3070-3075.
ABSTRACT | FULL TEXT  

Treating learning impairments improves memory performance in multiple sclerosis: a randomized clinical trial
Chiaravalloti et al.
Mult Scler 2005;11:58-68.
ABSTRACT  

Cognitive presentation of multiple sclerosis: evidence for a cortical variant
Zarei et al.
J. Neurol. Neurosurg. Psychiatry 2003;74:872-877.
ABSTRACT | FULL TEXT  

White Matter Changes in Schizophrenia: Evidence for Myelin-Related Dysfunction
Davis et al.
Arch Gen Psychiatry 2003;60:443-456.
ABSTRACT | FULL TEXT  

The Adult Memory and Information Processing Battery (AMIPB) test of information-processing speed: a study of its reliability and feasibility in patients with multiple sclerosis
Vlaar and Wade
Clin Rehabil 2003;17:386-393.
ABSTRACT  

Diffusion Tensor MR Imaging of Gray Matter in Different Multiple Sclerosis Phenotypes
Nusbaum
Am. J. Neuroradiol. 2002;23:899-900.
FULL TEXT  

Comparison of two brief neuropsychological batteries in people with multiple sclerosis
Solari et al.
Mult Scler 2002;8:169-176.
ABSTRACT  

The relation between objective and subjective impairment in cognitive function among multiple sclerosis patients - the role of depression
Maor et al.
Mult Scler 2001;7:131-135.
ABSTRACT  

Regional Magnetic Resonance Imaging Lesion Burden and Cognitive Function in Multiple Sclerosis: A Longitudinal Study
Sperling et al.
Arch Neurol 2001;58:115-121.
ABSTRACT | FULL TEXT  

Electroencephalographic coherence analysis in multiple sclerosis: correlation with clinical, neuropsychological, and MRI findings
Leocani et al.
J. Neurol. Neurosurg. Psychiatry 2000;69:192-198.
ABSTRACT | FULL TEXT  

Visuoperceptual impairment in multiple sclerosis patients diagnosed with neuropsychological tasks
Vleugels et al.
Mult Scler 2000;6:241-254.
ABSTRACT  

Assessment of cognitive and psychological functions in patients with multiple sclerosis: considerations for databasing
Beatty
Mult Scler 1999;5:239-243.
ABSTRACT  

Neuropsychologic Status in Multiple Sclerosis After Treatment With Glatiramer
Weinstein et al.
Arch Neurol 1999;56:319-324.
ABSTRACT | FULL TEXT  

Neurophysiological and cognitive markers of disease evolution in multiple sclerosis
Comi et al.
Mult Scler 1998;4:260-265.
ABSTRACT  

Computer assisted retraining of attentional impairments in patients with multiple sclerosis
Plohmann et al.
J. Neurol. Neurosurg. Psychiatry 1998;64:455-462.
ABSTRACT | FULL TEXT  

Screening for Cognitive Dysfunction in Multiple Sclerosis
Basso et al.
Arch Neurol 1996;53:980-984.
ABSTRACT  

Demographic, Clinical, and Cognitive Characteristics of Multiple Sclerosis Patients Who Continue to Work
Beatty et al.
Neurorehabil Neural Repair 1995;9:167-173.
ABSTRACT  

What Do We Really Know About Cognitive Dysfunction, Affective Disorders, and Stress in Multiple Sclerosis? A Practitioner's Guide
Fischer et al.
Neurorehabil Neural Repair 1994;8:151-164.
ABSTRACT  

Issues and Developments in the Neuropsychological Assessment of Patients with Multiple Sclerosis
Beatty and Scott
Neurorehabil Neural Repair 1993;7:87-97.
 

Posters (P1-P44)
Clin Rehabil 1992;6:61-82.
 

Cognitive Deficits and Emotional Dysfunction in Multiple Sclerosis
Herndon
Arch Neurol 1990;47:18-18.
ABSTRACT