 |
|
Perineural Spread of Cutaneous Head and Neck Cancer Its Orbital and Central Neurologic Complications
Paul D. Clouston, MBBS;
David M. Sharpe, MBBS, MRCP;
Alastair J. Corbett, MD, FRACP;
Susan Kos, MBBS, FRACR;
Peter J. Kennedy, MBBS, MDS, FRACS
Arch Neurol. 1990;47(1):73-77.
Abstract
• The ability of cutaneous squamous cell carcinoma of the face to cause ophthalmoplegia or central nervous system dysfunction via perineural spread is not well recognized. Five patients presenting to a general neurology unit are described in whom partial or complete ophthalmoplegia developed following fifth and seventh cranial nerve involvement by cutaneous squamous cell carcinoma. Two patients subsequently developed a contralateral hemiparesis; and one, multiple cranial nerve palsies as the tumor spread centrally. Normal radiologic findings or complete healing of the primary skin lesion caused delay in the diagnosis in three of the patients. When ophthalmoplegia or central nervous system dysfunction develops as a consequence of perineural spread of cutaneous facial cancer, management is palliative.
Author Affiliations
From the Departments of Neurology (Drs Clouston, Sharpe, and Corbett), Radiology (Dr Kos), and Head and Neck Surgery (Dr Kennedy), Repatriation General Hospital, Concord, Sydney, Australia.
Footnotes
Accepted for publication May 22, 1989.
Presented in part at the annual meeting of the Australian Association of Neurologists, Adelaide, South Australia, May 2,1989.
Reprint requests to Department of Neurology, Repatriation General Hospital, Hospital Road, Concord, NSW 21397 Australia (Dr Corbett).
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter
What's this?
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
Trigeminal neuropathy secondary to perineural invasion of head and neck carcinomas
Boerman et al.
Neurology 1999;53:213-213.
ABSTRACT
| FULL TEXT
Neurotropic Cutaneous Tumors of the Head and Neck
Osguthorpe et al.
Arch Otolaryngol Head Neck Surg 1997;123:871-876.
ABSTRACT
|
