This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Douglas Galasko, MD; Melville R. Klauber, PhD; C. Richard Hofstetter, PhD; David P. Salmon, PhD; Bruce Lasker, MD; Leon J. Thal, MD

Arch Neurol. 1990;47(1):49-52.

Abstract
• The Mini-Mental State Examination (MMSE), a brief test of cognitive function, has been widely used to screen for dementia. We administered the MMSE to 74 community-dwelling patients meeting criteria for probable Alzheimer's disease (AD) and 74 age- and education-matched controls. Twenty-four patients with AD performed in the nondemented range by scoring above the recommended cutoff point of 23 of a possible 30 on the MMSE. We compared the scores for items of the MMSE in controls and subjects with AD and used logistic regression to model a shorter MMSE that retained the accuracy of the complete test. A score summing tests of recall and orientation for place had similar sensitivity to the full MMSE. Adding a verbal fluency test to the MMSE reduced the error rate by improving the accuracy of diagnosis of patients with AD scoring in the nondemented range.

Author Affiliations
From the Departments of Neurosciences (Drs Galasko, Lasker, and Thal), Family and Community Medicine (Dr Klauber), and Psychiatry, (Dr Salmon), University of California, San Diego, Veterans Administration Medical Center; and the Department of Political Science, San Diego State University (Dr Hofstetter).

Footnotes
Accepted for publication June 2, 1989.

Reprint requests to Neurology Service (127), Veterans Administration Medical Center, 3350 La Jolla Village Dr, San Diego, CA 92161 (Dr Thal).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Self administered cognitive screening test (TYM) for detection of Alzheimer's disease: cross sectional study
Brown et al.
BMJ 2009;338:b2030-b2030.
ABSTRACT | FULL TEXT  

Brief Screening for Mild Cognitive Impairment in Elderly Outpatient Clinic: Validation of the Korean Version of the Montreal Cognitive Assessment
Lee et al.
J Geriatr Psychiatry Neurol 2008;21:104-110.
ABSTRACT  

Patient Age Influences Recognition of Alzheimer's Disease
McCarten et al.
Journals of Gerontology Series A: Biological Sciences and Medical Sciences 2008;63:625-628.
ABSTRACT | FULL TEXT  

Determinants of Mobility and Self-care in Older People With Stroke: Importance of Somatosensory and Perceptual Functions
Welmer et al.
ptjournal 2007;87:1633-1641.
ABSTRACT | FULL TEXT  

Can You Have Dementia With an MMSE Score of 30?
Shiroky et al.
AM J ALZHEIMERS DIS OTHER DEMEN 2007;22:406-415.
ABSTRACT  

Detrimental Effects of Tumor Progression on Cognitive Function of Patients With High-Grade Glioma
Brown et al.
JCO 2006;24:5427-5433.
ABSTRACT | FULL TEXT  

Psychometric Properties of the Folstein Mini-Mental State Examination
Lopez et al.
Assessment 2005;12:137-144.
ABSTRACT  

Apolipoprotein {varepsilon}4 Allele and Problems With Orientation Are Associated With a Persistent Decline in Cognition in Community-Dwelling Elderly Persons
Wayne et al.
Journals of Gerontology Series A: Biological Sciences and Medical Sciences 2005;60:375-379.
ABSTRACT | FULL TEXT  

The neurocognitive effects of radiation in adult low-grade glioma patients
Brown et al.
Neuro Oncol Duke 2003;5:161-167.
ABSTRACT  

Effects of Radiotherapy on Cognitive Function in Patients With Low-Grade Glioma Measured by the Folstein Mini-Mental State Examination
Brown et al.
JCO 2003;21:2519-2524.
ABSTRACT | FULL TEXT  

MMSE Items Predict Cognitive Decline in Persons with Genetic Risk for Alzheimer's Disease
Ercoli et al.
J Geriatr Psychiatry Neurol 2003;16:67-73.
ABSTRACT  

An exploratory study of the consistency of balance control and the mobility of people with Parkinson's disease (PD) between medication doses
Campbell et al.
Clin Rehabil 2003;17:318-324.
ABSTRACT  

Errors Produced on the Mini-Mental State Examination and Neuropsychological Test Performance in Alzheimer's Disease, Ischemic Vascular Dementia, and Parkinson's Disease
Jefferson et al.
J. Neuropsychiatry Clin. Neurosi. 2002;14:311-320.
ABSTRACT | FULL TEXT  

Greek validation of the Seven-Minute Screening Battery for Alzheimer's disease in the elderly
Tsolaki et al.
AM J ALZHEIMERS DIS OTHER DEMEN 2002;17:139-148.
ABSTRACT  

Delayed discharges from Oxford city hospitals: who and why?
Carter and Wade
Clin Rehabil 2002;16:315-320.
ABSTRACT  

Cortical and subcortical contributions to ideomotor apraxia: Analysis of task demands and error types
Hanna-Pladdy et al.
Brain 2001;124:2513-2527.
ABSTRACT | FULL TEXT  

A 5-Year Retrospective Examination of Cognitive Screening Test Stages in Normal Older Adults and Patients With Alzheimer's Disease: The Tajiri Project
Meguro et al.
Journals of Gerontology Series B: Psychological Sciences and Social Science 2001;56:P314-318.
ABSTRACT | FULL TEXT  

A pilot study of attention deficits, balance control and falls in the subacute stage following stroke
Stapleton et al.
Clin Rehabil 2001;15:437-444.
ABSTRACT  

Mild Cognitive Impairment Represents Early-Stage Alzheimer Disease
Morris et al.
Arch Neurol 2001;58:397-405.
ABSTRACT | FULL TEXT  

Prediction of Probable Alzheimer Disease in Patients With Symptoms Suggestive of Memory Impairment: Value of the Mini-Mental State Examination
Tierney et al.
Arch Fam Med 2000;9:527-532.
ABSTRACT | FULL TEXT  

The Course of Cognitive Impairment in Preclinical Alzheimer Disease: Three- and 6-Year Follow-up of a Population-Based Sample
Small et al.
Arch Neurol 2000;57:839-844.
ABSTRACT | FULL TEXT  

Evidence for cortical dysfunction in clinically non-demented patients with Parkinson's disease: a proton MR spectroscopy study
Hu et al.
J. Neurol. Neurosurg. Psychiatry 1999;67:20-26.
ABSTRACT | FULL TEXT  

Variability in Annual Mini-Mental State Examination Score in Patients With Probable Alzheimer Disease: A Clinical Perspective of Data From the Consortium to Establish a Registry for Alzheimer's Disease
Clark et al.
Arch Neurol 1999;56:857-862.
ABSTRACT | FULL TEXT  

Norms for the Mini-Mental State Examination in a healthy population
Grigoletto et al.
Neurology 1999;53:315-315.
ABSTRACT | FULL TEXT  

Attention and executive deficits in Alzheimer's disease: A critical review
Perry and Hodges
Brain 1999;122:383-404.
ABSTRACT | FULL TEXT  

Head injuries and cognitive decline among older adults: A population-based study
Luukinen et al.
Neurology 1999;52:557-557.
ABSTRACT | FULL TEXT  

Sex and relationship dysfunction in neurological disability
Chandler and Brown
J. Neurol. Neurosurg. Psychiatry 1998;65:877-880.
ABSTRACT | FULL TEXT  

North of England evidence based guidelines development project: guideline for the primary care management of dementia
Eccles et al.
BMJ 1998;317:802-808.
FULL TEXT  

Randomised controlled trial comparing hospital at home care with inpatient hospital care. I: three month follow up of health outcomes
Shepperd et al.
BMJ 1998;316:1786-1791.
ABSTRACT | FULL TEXT  

A 7 Minute Neurocognitive Screening Battery Highly Sensitive to Alzheimer's Disease
Solomon et al.
Arch Neurol 1998;55:349-355.
ABSTRACT | FULL TEXT  

Central Auditory Dysfunction, Cognitive Dysfunction, and Dementia in Older People
Gates et al.
Arch Otolaryngol Head Neck Surg 1996;122:161-167.
ABSTRACT  

Clinical Validity of the Mattis Dementia Rating Scale in Detecting Dementia of the Alzheimer Type: A Double Cross-Validation and Application to a Community-Dwelling Sample
Monsch et al.
Arch Neurol 1995;52:899-904.
ABSTRACT  

Discrimination Between Stages of Alzheimer's Disease With Subsets of Mini-Mental State Examination Items: An Analysis of Consortium to Establish a Registry for Alzheimer's Disease Data
Fillenbaum et al.
Arch Neurol 1994;51:916-921.
ABSTRACT  

Agraphia in Dementia of the Alzheimer Type
LaBarge et al.
Arch Neurol 1992;49:1151-1156.
ABSTRACT  

Establishing the Limits of the Mini-Mental State: Examination of 'Subtests'
Feher et al.
Arch Neurol 1992;49:87-92.
ABSTRACT  

Quantifying Radiation Therapy-induced Brain Injury with Whole-Brain Proton MR Spectroscopy: Initial Observations
Movsas et al.
Radiology 2001;221:327-331.
ABSTRACT | FULL TEXT