 |
|
Normal Cerebrospinal Fluid DynamicsA Study With Intraventricular Injection of 111In-DTPA in Leukemia and Lymphoma Without Meningeal Involvement
Hanny Haaxma-Reiche, MD, PhD;
Do Albertus Piers, MD, PhD;
Henk Beekhuis, MD, PhD
Arch Neurol. 1989;46(9):997-999.
Abstract
• The cerebrospinal fluid flow pattern in seven patients with leukemia or lymphoma, but without prior meningeal or cerebral disease, was studied following introduction of indium-diethylenetriamine pentaacetic acid In-DTPA 111 in a lateral ventricle through an Ommaya reservoir. The time to egress from the ventricular system into the basal cisterns was variable but generally short. One hour after administration, the basal cisterns were clearly visible in all patients. Thereafter, kinetics throughout the cranial and spinal subarachnoid space were consistent. The flow patterns of three patients cured of meningeal dissemination and one patient with mild meningeal leukemia were similar to the normal pattern.
Author Affiliations
From the Departments of Neurology (Dr Haaxma-Reiche) and Nuclear Medicine (Drs Piers and Beekhuis), University of Groningen, the Natherlands.
Footnotes
Accepted for publication February 16, 1989.
Reprint requests to Department of Neurology, University Hospital, Oostersingel 59, 9713 EZ Groningen, the Netherlands (Dr Haaxma-Reiche).
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter
What's this?
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
111Indium-diethylenetriamine pentaacetic acid CSF flow studies predict distribution of intrathecally administered chemotherapy and outcome in patients with leptomeningeal metastases
Chamberlain et al.
Neurology 1999;52:214-214.
FULL TEXT
|
