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  Vol. 46 No. 8, August 1989 TABLE OF CONTENTS
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Neurophysiological Evidence of Auditory Channel Anomalies in Developmental Dysphasia

Gerry A. Stefanatos, DPhil; Gary G. R. Green, DPhil, BM, BCh; Graham G. Ratcliff, DPhil

Arch Neurol. 1989;46(8):871-875.


Abstract

• Steady-state auditory evoked responses to frequency-modulated tones were obtained from normal children and two groups of children with developmental language disorders (developmental dysphasia). Children with predominantly expressive language impairment produced responses not different from normal children, while children with primary receptive language impairment produced responses that were markedly diminished, even absent. This occurred in recordings from either cerebral hemisphere and at mean frequency-modulation depths ranging from ± 20 to ±100 Hz. Pathophysiology of auditory mechanisms concerned with frequency-modulation analysis are particularly associated with receptive developmental language impairment and may underlie associated difficulties in speech perception.



Author Affiliations

From the Neuropsychology Unit, Oxford (England) University Department of Clinical Neurology, Radcliffe Infirmary, Oxford (Dr Stefanatos), and the Department of Physiological Sciences, The Medical School, University of Newcastle upon Tyne, Newcastle, England (Dr Green); and the Departments of Neurology, Psychiatry, and Psychology, University of Pittsburgh (Pa) (Dr Ratcliff). Dr Stefanatos is now with the Medical College of Pennsylvania, Philadelphia.


Footnotes

Accepted for publication February 6, 1989.

Reprint requests to the Division of Child Psychiatry, Medical College of Pennsylvania, 3200 Henry Ave, Philadelphia, PA 19129 (Dr Stefanatos).



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