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Clinical and Pharmacologic Findings in 21 Patients

Richard B. Dewey, Jr; Joseph Jankovic, MD

Arch Neurol. 1989;46(8):862-867.

Abstract
• In this series of 21 patients with hemiballism-hemichorea we found an identifiable cause in all. Unlike most other studies in which stroke was the most important cause of the movement disorder, in almost half (10 of 21) of our patients some other cause was found. Hemiballismhemichorea was often the presenting feature of underlying medical disease. Besides the subthalamic nucleus, other subcortical structures may be involved in the pathogenesis of this hemihyperkinesia. While the movement disorder often improves spontaneously or with pharmacologic therapy, the underlying disease may result in serious consequences.

Author Affiliations
From the Department of Neurology, Baylor College of Medicine, Houston, Tex.

Footnotes
Accepted for publication January 3, 1989.

Reprint requests to Department of Neurology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030 (Dr Jankovic).

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