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Clinical and Postmortem Findings

Gordon Banks, PhD, MD; Priscilla Short, MD; A. Julio Martínez, MD; Richard Latchaw, MD; Graham Ratcliff, DPhil; François Boller, MD, PhD

Arch Neurol. 1989;46(4):456-459.

Abstract
• Two patients had automatonlike movements of their left hands and arms (alien hand syndrome) following damage to the brain. Autopsy findings in one patient demonstrated gunshot wound damage to the medial frontal white matter bilaterally, as well as the corpus callosum, right basal ganglia, internal capsule, and thalamus. The other patient had a ruptured anterior communicating aneurysm, with subsequent resection of the right frontal gyrus rectus. We postulate that this syndrome is due to the combination of a partial callosectomy and mesial frontal lesions.

Author Affiliations
From the Departments of Neurology (Drs Banks, Short, and Boller), Pathology (Dr Martínez), Radiology (Dr Latchaw), Psychology (Dr Ratcliff), and Psychiatry (Drs Ratcliff and Boller), University of Pittsburgh; and Harmarville Rehabilitation Center, Pittsburgh (Dr Ratcliff).

Footnotes
Accepted for publication Feb 15, 1988.

Read before the 30th annual meeting of the American Academy of Neurology, Boston, April 10, 1984.

Reprint requests to Department of Neurology, University of Pittsburgh, 322 Scaife Hall, Pittsburgh, PA 15261 (Dr Banks).

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