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Omkar N. Markand, MD, FRCPC; Martin R. Farlow, MD; James C. Stevens, MD; Mary K. Edwards, MD

Arch Neurol. 1989;46(3):295-299.

Abstract
• We correlated the brain-stem auditory evoked potential (BAEP) abnormalities in 24 patients with discrete unilateral brain-stem lesions demonstrated by magnetic resonance imaging. In 18 patients who had BAEP abnormalities either confined to or more severe on stimulation of one ear, the lesion on magnetic resonance imaging was in the brain stem ipsilateral to the corresponding ear. Mesencephalic lesions produced amplitude abnormalities of the IV/V complex while pontine lesions resulted in abnormalities of earlier components (wave II and/or III). Prolongation of the I-III interpeak latencytended to occur with pontine lesions and of the III-V interpeak latency with mesencephalic lesions. Unilateral brain-stem lesions, particularly at the mesencephalic level, often produced BAEP abnormalities on both ipsilateral and contralateral monaural stimulation.

Author Affiliations
From the Departments of Neurology (Drs Markand, Farlow, and Stevens) and Radiology (Dr Edwards), Indiana University School of Medicine, Indianapolis.

Footnotes
Accepted for publication July 8, 1988.

Reprint requests to the Department of Neurology, 702 Barnhill Dr, Indianapolis, IN 46223 (Dr Markand).

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ABSTRACT