Neurologic involvement in Behcet's syndrome. A prospective study

P. Serdaroglu, H. Yazici, C. Ozdemir, S. Yurdakul, S. Bahar and E. Aktin
Department of Neurology, Istanbul Medical Faculty, Turkey.

We investigated the prevalence and type of neurologic involvement in Behcet's syndrome in a prospective protocol. Of 323 consecutive patients with Behcet's syndrome seen during a 12-month period, 46 underwent neurologic evaluation because of headaches and/or neurologic symptoms and signs. Only 17 (5.3%) were found to have involvement of the nervous system. Hemispheric lesions were as common as brain-stem involvement. Headaches were of no clinical importance unless accompanied by other neurologic findings. Computed tomographic scans were of little diagnostic help. After 12 +/- 4 (SD) months of follow-up, only three patients showed worsening of their neurologic findings.

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