Magnetic resonance imaging in a family with hereditary cerebral arteriovenous malformations
J. C. Allard, F. H. Hochberg, P. D. Franklin and A. P. Carter
Department of Radiology, Boston University, MA.
Because of a family history of neurologic problems and the documentation of
three vascular lesions in one patient, we evaluated 18 members representing
three family generations with magnetic resonance imaging. Of these, eight
were normal, two had abnormalities probably not related to arteriovenous
malformation, one scan was suboptimal, and the remaining eight had evidence
of hemorrhagic lesions characteristic of arteriovenous malformation. Four
of these patients had multiple lesions, and three patients with lesions had
no neurologic symptoms. The findings suggest an autosomal dominant mode of
inheritance in this unique case of familial cerebral arteriovenous
malformation.
