This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Short Course of Treatment With Albendazole

Fernando Alarcón, MD; Luis Escalante, MD; Gonzalo Dueñas, MD; Magalit Montalvo, MD; Marcelo Román, MD

Arch Neurol. 1989;46(11):1231-1236.

Abstract
• Eighteen patients with nonenhancing parenchymal brain cysts were treated with albendazole; 9 patients were treated for 3 days and 9 patients for 1 month at daily doses of 15 mg/kg of body weight. Three months after starting therapy, results showed that in both groups the treatment was highly effective. Control studies carried out in the same group before the trial did not show any significant improvement. Five patients were controls and were treated only with symptomatic drugs. The total diameter of the lesions was reduced from 220.1 mm to 52.1 mm, which signifies a reduction of 76.3% in patients treated for a period of 3 days, and from 278.5 mm to 82.1 mm, which is 70.5%, in patients treated for 30 days. We conclude that albendazole administered according to the 3-day therapeutic scheme proposed above is as highly effective for the treatment of parenchymal brain cysticercosis as the 30-day scheme.

Author Affiliations
From the Departments of Neurology (Drs Alarcón, Montalvo, and Román) and Neuroradiology (Dr Dueñas), Eugenio Espejo Hospital, and the Immunology Department, National Institute of Hygiene and Tropical Medicine (Dr Escalante), Quito, Ecuador.

Footnotes
Accepted for publication April 20, 1989.

Reprint requests to Department of Neurology, Eugenio Espejo Hospital, Casilla 8991, Sucursal 7, Quito, Ecuador (Dr Alarcón).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Meta-Analysis: Cysticidal Drugs for Neurocysticercosis: Albendazole and Praziquantel
Del Brutto et al.
ANN INTERN MED 2006;145:43-51.
ABSTRACT | FULL TEXT  

Current Consensus Guidelines for Treatment of Neurocysticercosis
Garcia et al.
Clin. Microbiol. Rev. 2002;15:747-756.
ABSTRACT | FULL TEXT  

Albendazole therapy for subarachnoid cysticerci: clinical and neuroimaging analysis of 17 patients
CARPIO; and DEL BRUTTO
J. Neurol. Neurosurg. Psychiatry 1999;66:411a-412.
FULL TEXT  

Is the Course of Neurocysticercosis Modified by Treatment With Anthelmintic Agents?
Del Brutto
Arch Intern Med 1997;157:128-129.
ABSTRACT  

Is the Course of Neurocysticercosis Modified by Treatment With Antihelminthic Agents?
Carpio et al.
Arch Intern Med 1995;155:1982-1988.
ABSTRACT  

Topical Review: Parasitic Infections of the Central Nervous System in Children. Part III: Space-Occupying Lesions
Lowichik and Ruff
J Child Neurol 1995;10:177-190.
ABSTRACT  

Medical Treatment of Cysticercosis--Ineffective
Kramer
Arch Neurol 1995;52:101-102.
ABSTRACT  

Albendazole Therapy for Giant Subarachnoid Cysticerci
Brutto et al.
Arch Neurol 1992;49:535-538.
ABSTRACT  

Therapy for Neurocysticercosis: Comparison Between Albendazole and Praziquantel
Takayanagui and Jardim
Arch Neurol 1992;49:290-294.
ABSTRACT  

Albendazole Therapy for Neurocysticercosis
Del Brutto
Arch Neurol 1990;47:1278-1278.
ABSTRACT  

Albendazole Therapy for Neurocysticercosis-Reply
Alarcon
Arch Neurol 1990;47:1278-1279.
ABSTRACT  

Antihelminthic Therapy for Neurocysticercosis
Kramer
Arch Neurol 1990;47:1059-1059.
ABSTRACT  

Antihelminthic Therapy for Neurocysticercosis-Reply
Alarcon et al.
Arch Neurol 1990;47:1060-1060.
ABSTRACT