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Ashfaq Shuaib, MD; Vladimir C. Hachinski, MD

Arch Neurol. 1988;45(8):911-912.

Abstract
• There is some suggestion in the literature that patients with migraine may be at an increased risk for developing complications as a result of cerebral angiography. To assess this risk, we reviewed the charts of 142 patients with migraine. A total of 149 angiograms were performed for acute headache (55), new focal symptoms (40), exertional (including coital) headaches (nine), hemiplegic migraine (three), ophthalmoplegic migraine (five), vertebrobasilar migraine (six), migraine accompaniments (three), and other causes (14). Transient events were seen in six patients and these were transient amnesia (one), hemisensory changes (two), hemiparesis (one), global confusion (one), and angina (one). One patient with a history of severe ischemic heart disease developed a myocardial infarction two hours after angiography. Focal cerebral events occurred in 2.6% of cases. This compares wiht a rate of complications of 2.8% caused by angiography in a prospective study of 1002 patients from our center. According to our findings, it appears that a history of migraine does not increase the risk of complications caused by angiography. Angiography during episodes of acute headaches would also appear to be a safe procedure. Transient focal neurologic symptoms, however, are not infrequent, especially in cases of classic migraine.

Author Affiliations
From the Department of Clinical Neurological Sciences, University Hospital, London, Ontario. Dr Shuaib is now with the Department of Clinical Neurosciences, Foothills Hospital, Calgary, Alberta.

Footnotes
Accepted for publication March 21, 1988.

Reprint requests to Department of Clinical Neurological Sciences, Room 7GE5, University Hospital, PO Box 5339, Postal Station A, London, Ontario, Canada N6A 5A5 (Dr Hachinski).

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