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The Relationship of Agraphia to the Severity of Dementia in Alzheimer's Disease
ennifer Horner, PhD;
Albert Heyman, MD;
Deborah Dawson, PhD;
Helen Rogers, PhD
Arch Neurol. 1988;45(7):760-763.
Abstract
• Impairment of writing ability was studied in 20 patients with mild to moderate dementia caused by early-onset Alzheimer's disease. A multicomponent analysis was made of a brief narrative writing sample obtained from each patient, and this writing proficiency score was compared with results of standard tests of cognitive function as well as ratings of the degree of dementia. In these patients, significant correlations were observed between this brief test of narrative writing ability and the severity of dementia. An analysis of writing proficiency appears to be a simple means of assessing the severity of dementia caused by Alzheimer's disease. Further studies are needed to show the potential usefulness of such measures of agraphia in subtyping this disease.
Author Affiliations
From the Department of Surgery and Center for the Study of Aging and Human Development, Duke University Medical Center, and the Audiology-Speech Pathology Service, Durham Veterans Administration Medical Center (Dr Horner); the Division of Neurology, Department of Medicine, The Joseph and Kathleen Bryan Alzheimer's Disease Research Center (Drs Heyman, Dawson, and Rogers); and the Division of Biometry, Department of Community and Family Medicine, Duke University Medical Center (Dr Dawson), Durham, NC.
Footnotes
Accepted for publication Nov 17, 1987.
Reprint requests to Department of Surgery, Box 3887, Duke University Medical Center, Durham, NC 27710 (Dr Horner).
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