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David A. Krendel, MD; James M. Gilchrist, MD; Edward H. Bossen, MD

Arch Neurol. 1988;45(6):698-699.

Abstract
• We describe a 26-year-old man with a predominantly distal myopathy and complete heart block. A muscle biopsy specimen demonstrated numerous vacuoles, which, by electron microscopy, contained membranous whorls. Filamentous inclusions characteristic of inclusion body myositis were not seen. It is important to be aware that life-threatening cardiac disease may occur in this setting.

Author Affiliations
From the Department of Internal Medicine, Division of Neurology (Drs Krendel and Gilchrist), and the Department of Pathology (Dr Bossen), Duke University Medical Center, Durham, NC. Dr Krendel is presently with the Department of Neurology, Emory University School of Medicine, Atlanta.

Footnotes
Accepted for publication Dec 21, 1987.

Reprint requests to Department of Neurology, Emory University School of Medicine, 80 Butler St SE, Atlanta, GA 30335 (Dr Krendel).

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